Breakthrough in Childhood Brain Tumour Research

You are driving life-changing research.

Thanks to your incredible generosity, Dr Yannan Yang and his dedicated team have been awarded a prestigious $840,000 Medical Research Future Fund (MRFF) grant. This critical funding will help advance new treatments for diffuse intrinsic pontine glioma (DIPG), a rare, aggressive and currently inoperable childhood brain tumour with no known cure.

A New Era of Hope for DIPG

DIPG remains one of the most heartbreaking diagnoses in childhood cancer. Its location in the brainstem makes surgery impossible, and current treatments provide only limited relief.

One of the most promising treatment avenues, CAR-T cell immunotherapy, has shown real potential. But DIPG tumours are complex and highly variable, often managing to evade detection and resist existing treatments.

That’s where your support is making a truly groundbreaking difference.

Thanks to your generosity, Dr Yang and his team have developed an innovative vaccine-based nanotechnology approach. This new therapy works by “training” the immune system using tumour-specific antigens, delivered via nanocarriers, with the goal of making treatments more targeted, more effective and longer lasting. It’s a pioneering strategy that offers new hope for children and families impacted by this devastating disease.

Your Support Made This Possible

This achievement didn’t happen by chance. It’s the result of years of hard work, collaboration and innovation – all made possible by the early seed funding you helped provide.

Your belief in a better future for children with DIPG laid the foundation for this major breakthrough. And now, because of you, the next phase of this vital research is already underway.

Every Step Forward Is Because of You

Your continued support drives every advance, every new discovery, and every bit of hope for families facing DIPG. This isn’t just a scientific milestone – it’s a message of hope.

Together, we are changing the future.

Be Part of the Next Breakthrough

The road ahead is still long, but we are closer than ever to real change. Will you help continue this life-changing research?

Donate today. Your support can be the start of the next breakthrough.